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Factsheet

Ketamine

Ketamine hydrochloride is a dissociative anaesthetic. It is used primarily in veterinary settings as a short-acting anaesthetic. Ketamine is used for limited medical applications on humans because it does not depress breathing or circulation (in lower dosage). The use of ketamine for recreational use is illegal.

Last updated: 21 September 2010

What is Ketamine?

Ketamine hydrochloride is a dissociative anaesthetic. It is used primarily in veterinary settings as a short-acting anaesthetic. Ketamine is used for limited medical applications on humans because it does not depress breathing or circulation (in lower dosage). The use of ketamine for recreational use is illegal.

Street names include: Special K, K, Cat Tranquilizer, ket, Ketaset, ketalor, kitkat, super K, Vitamin K, Lady K.

How is it used?

Ketamine is a white crystalline powder. It can be made into tablets and pills or dissolved in a liquid. Ketamine is often swallowed, snorted or injected. It is also sometimes smoked with other substances such as cannabis or tobacco.

Ketamine is used recreationally as a snorted white powder and for therapeutic and psychedelic use it is often injected intra-muscularly (IM). Ketamine has also been implicated as a drug used to facilitate sexual assault.

Effects

Low to moderate dose can induce the following effects:

• Impaired motor coordination
• blurred vision
• constricted pupils
• euphoria and relaxation
• feelings of dissociation (being detached from the body)
• hallucinations and distorted sensory processing, including visual, auditory, bodily, time and space perception
• disorganised thoughts, confusion and difficulty concentrating, thinking or maintaining attention
• anxiety, agitation, paranoia and feelings of panic
• slurred speech
• Increased libido
• increased heart rate and blood pressure
• breathing rate increased but shallow
• nausea and vomiting
• sweating
• reduced sensitivity to pain and numbness of the extremities.


Higher doses

• drowsiness
• erratic, hostile and bizarre behaviour
• feelings of panic and terror
• paranoia
• depression
• amnesia
• anaesthesia
• muscle rigidity
• hypersalivation
• increased body temperature or fever
• cardiac arrhythmia
• convulsions
• coma
• "near death" experience
• risk of accidents.

Some users have extremely unpleasant experiences with ketamine, which are sometimes known as "bad trips".

People who use ketamine may fall into an anaesthetised state, a 'k-hole'.The experience of being in a k-hole varies but generally involves being socially detached, having hallucinations and experiencing a distorted sense of time and space.

One of the more serious effects of using ketamine is that a user may harm themselves. There is the potential for people to cut or burn themselves unknowingly while using the drug.

Immediate effects

The effects of ketamine may be experienced within 30 seconds (if taken intravenously) to 20 minutes (if taken orally) and can last for one to three hours.

Long-term effects

Some regular users experience flashbacks - the spontaneous recurrence of an experience that occurred while the user was under the influence of the drug. Flashbacks can occur days, weeks or months after a person has used ketamine.

There is also some emerging evidence that repeated use may impair some aspects of memory and cognitive functions.

Long-term, frequent use of ketamine has been linked to personality and mood changes including paranoia and egocentrism, reduced ability to concentrate and depression.

Mixing with other drugs

Combining ketamine with depressants such as alcohol, tranquillisers or GHB can slow down the body's central nervous system and is dangerous. At higher doses ketamine depresses consciousness and breathing and overdose is a significant risk when combined with depressants.

Tolerance and dependence

Tolerance to ketamine can develop very quickly, with people needing more and more to achieve the same euphoric and psychedelic effects.

People who regularly use ketamine can develop a physical and psychological dependence. A person who uses it regularly may find it difficult to stop.

Withdrawal

There is currently little evidence to support the view that people who are dependent on ketamine experience physical withdrawal symptoms if they suddenly stop taking it.

Pregnancy and breastfeeding

Little is known about the effects of ketamine on the unborn child. Most drugs have some effect on the unborn baby if the mother uses them and it is not recommended that people use ketamine while pregnant or breastfeeding.

The Law

Using ketamine, or keeping, selling or giving it to someone else is illegal. If you are caught you could face substantial fines and penalties including a prison sentence.

Driving

It is not safe to drive while using ketamine. Drowsiness, impaired motor coordination, and hallucinations can affect the ability to drive.

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