This procedure describes the process of receipting, storing, transporting and drawing up the COVID-19 ComirnatyTM (Pfizer) dilute to use (concentrate) multidose for 5 to ˂12 years of age formulation vaccine (Comirnaty (Pfizer) 5 to <12 years formulation vaccine) in NSW Health clinics.
Staff preparing the refrigerated Comirnaty (Pfizer) 5 to <12 years formulation vaccine for administration must follow this procedure. When working in pairs, it is the responsibility of both people to continue to follow this procedure and observe all local COVID-19 precautions, including maintaining social distancing where possible.
The Comirnaty (Pfizer) 5 to <12 years formulation vaccine must be thawed before use following removal from an ultra-low temperature storage environment.
Once thawed, the Comirnaty concentrate vaccine vial must not be returned to an ultra-low temperature environment for re-freezing. A closed lid vial carton can be stored at +2 to +8°C for up to 10 weeks.
Each vial carton contains 10 vials. If removing less than the full quantity of vials from the carton within the refrigerator, ensure that the carton remains enclosed, after removal of the required number of vials. Note each vial provides 10 doses when using low dead space needles and syringes for drawing up.
An equipment sparing strategy is to extract 7 doses using low dead space needles and syringes, and 3 doses using 1mL tuberculin syringes and 25G needles.
This procedure covers the process from the removal of vials of thawed concentrate vaccine from the vial carton in the refrigerator, dilution of the concentrate vaccine, and drawing up individual doses into a syringe to the point of administration.
This procedure may be adapted to suit one of the following models: