Staff preparing the Moderna elasomeran (SpikevaxTM) COVID-19 vaccine for administration must follow this procedure. When working in pairs, it is the responsibility of both people to continue to follow this procedure and observe all local COVID-19 precautions, including maintaining social distancing where possible.
The Moderna elasomeran (SpikevaxTM) COVID-19 vaccine must be thawed before use following removal from a frozen storage environment. Refer to 'Management of COVID-19 Moderna (SPIKEVAX) vaccine from a standard temperature freezer to refrigerator' for information on this procedure.
Once thawed, the Moderna elasomeran (SpikevaxTM) COVID-19 vaccine must
not be re-frozen. Note the thawing process in a refrigerator (2°C to 8°C) takes 2 hours and 30 minutes or 1 hour at room temperature (15°C to 25°C).
A thawed vial can be stored at +2 to +8°C for 30 days.
Each carton contains 10 multidose vials. Each multidose vial contains 10 doses of 0.5mL. The vial DOES NOT require a diluent to be added. Once thawed the vaccine is ready to use.
The procedure used to draw up the vaccine will be dependent on the preferred drawing up method that has been agreed on for consistent use at the hub/clinic i.e. multiple puncture or single puncture technique. This technique should subsequently be consistently used by all individuals involved in the drawing up process in that hub/clinic.
Innovation Compounding - Proper Aseptic Technique to Prevent Coring of Sterile Vials
Where vaccines are prepared and administered by different staff the handover process must be clearly documented as per local guidelines.
For additional clinical advice including advice on interrupted doses and diluent leakage when reconstituting, see
COVID-19 vaccine – Clinical considerations.
1.C Syringe label (to be applied to each prepared syringe)