The JYNNEOS vaccine to protect against mpox (monkeypox) is free in NSW for eligible groups of people. You can be vaccinated without a Medicare card.

People who are recommended to be vaccinated against mpox can make an appointment by calling one of the clinics listed below.

For free help in your language, call the Translating and Interpreting Service on 13 14 50.

On this page

Who should be vaccinated?

The following people are recommended to be vaccinated against mpox:

  • all sexually active gay and bisexual men (cis and trans)
  • sexual partners of the people above
  • sex workers.

If this criteria applies to you, you can book your vaccine by calling one of the clinics listed below or walk in.

Anyone who has already received their first dose is recommended to receive their second dose if it is at least 28 days since their first dose.


If you recently received your first dose of vaccine and have a second dose appointment scheduled at either The Prevention Hub in Surry Hills after 18 March 2023 or St Vincent’s Hospital WorldPride Hub in Darlinghurst after 10 March 2023 – you will be contacted by clinic staff to reschedule your appointment.

In the unlikely event that you were uncontactable by clinic staff, you will need to call one of the clinics listed below to book your seond dose.

Book an appointment

Search for your nearest vaccination clinic in the list below.

To book an appointment, call the vaccination clinic or you can also walk in. You can call Sexual Health Infolink on 1800 451 624 for further vaccine booking support.

Sydney - Metro

City/suburbVaccination centre/clinicFor booking support
Camperdown Call RPA Sexual Health Clinic, 16 Marsden Street, Camperdown to make a booking(02) 9515 1200
DarlinghurstCall Kirketon Road Centre, above the Darlinghurst Fire Station, Victoria Street (entrance), Darlinghurst to make a booking(02) 9360 2766
Darlinghurst Call IBAC Clinic, St Vincent's Hospital, Level 4, Xavier Building, 390 Victoria Street, Darlinghurst to make a booking (02) 8382 3707
KogarahCall Short Street Centre Sexual Health Clinic, St George Hospital
Ground Floor, Prichard Wing Short Street, Kogarah to make a booking
(02) 9113 2742
KingswoodCall Nepean Sexual Health Clinic to make a booking(02) 4734 2507
LiverpoolCall Liverpool Sexual Health Clinic, 13 Elizabeth Street, Liverpool to make a booking (02) 9827 8022
ParramattaCall Western Sydney Sexual Health Centre, Parramatta Health Service, 162 Marsden Street, Parramatta to make a booking (02) 9843 3124
Surry HillsCall The Albion Centre, 150-154 Albion Street, Surry Hills to make a booking (02) 9332 9600
St LeonardsCall Clinic 16, Royal North Shore Community Health Centre, Level 5, 2C Herbert Street to make a booking(02) 9462 9500
Sydney CBDCall Sydney Sexual Health Clinic, Level 3, Nightingale Wing, Sydney Eye Hospital, 8 Macquarie Street, Sydney to make a booking (02) 9382 7440

NSW - Far West

City/suburbVaccination centreFor booking support
Broken HillCall Clinic 9, Broken Hill Sexual Health Clinic/Viral Hepatitis Clinic, 2-4 Sulphide Street, Broken Hill to make a booking(08) 8080 1100

NSW - Hunter New England

City/suburbVaccination clinicFor booking support
NewcastleCall Pacific Clinic, Newcastle Sexual Health, Level 2, 670 Hunter Street, Newcastle to make a booking(02) 4016 4536
TamworthCall Clinic 468, 468 Peel Street, Tamworth to make a booking(02) 6764 8080
TareeCall Taree Sexual Health Clinic, 64 Pulteney Street, Taree to make a booking(02) 4016 4536

NSW - North

City/suburbVaccination clinicFor booking support
LismoreCall Lismore Sexual Health Service, 4 Shepherd Lane, Lismore to make a booking(02) 6620 2980
Tweed HeadsCall Tweed Valley Sexual Health Service (Clinic 145), 145 Wharf Street, Tweed Heads to make a booking (07) 5506 6850

NSW - North Coast

City/suburbVaccination clinicFor booking support
Coffs HarbourCall Sexual Health Clinic (Clinic 916), Coffs Harbour Health Campus, 345 Pacific Highway to make a booking(02) 6656 7865
Port Macquarie Call Sexual Health (Clinic 33), Port Macquarie Community Health Centre, Morton Street to make a booking(02) 6589 2120
Select option 2 then option 6

NSW - South

City/suburbVaccination clinicFor booking support
AlburyCall Clinic 72, Sexual Health Service Albury Community Health Service, 596 Smollett Street, Albury to make a booking(02) 6058 1831
Wagga WaggaCall Brookong Centre, Sexual Health Service, Wagga Wagga Health Service Hub, Wagga Wagga Base Hospital, Wagga Wagga to make a booking(02) 5943 2830
QueanbeyanCall Queanbeyan Community Health Centre, corner of Erin Street and Collett Street, Queanbeyan to make a booking0427 893 247

NSW - South Coast

City/suburbVaccination clinicFor booking support
Port KemblaCall Illawarra Shoalhaven Sexual Health Service, Port Kembla Hospital to make a booking(02) 4223 8457
EurobodallaCall Moruya Hospital and Health Service, 2-10 River Street, Moruya to make a booking0427 219 874
BegaCall Bega Sexual Health and Hepatitis Service, South East Regional Hospital (SERH), 4 Virginia Drive, Bega to make a booking0427 219 874
Batemans BayCall Batemans Bay Hospital and Health Service, 7 Pacific Street, Batemans Bay to make a booking 0427 219 874

NSW - West

City/suburbVaccination clinicFor booking support
GriffithCall the Griffith Community Health Centre, 39 Yambil Street, Griffith to make a booking(02) 6966 9900

About mpox (monkeypox)

What is mpox?

Mpox is caused by a virus that is spread mainly through skin-to-skin contact, or close contact with someone who has mpox. In NSW, it is primarily affecting gay and bisexual men and other men who have sex with men. For more information, visit our mpox information hub.

NSW JYNNEOS vaccine rollout

NSW Health began vaccinating people at highest risk from mpox on 8 August 2022.

The JYNNEOS vaccine to protect against mpox is free in NSW and you can be vaccinated without Medicare.

NSW Health is working closely with partner agencies such as NSW Sexual Health Infolink and ACON on the vaccine rollout.

People who are recommended to receive the vaccine can book an appointment by calling one of the clinics listed on this page.

You can also call Sexual Health Infolink on 1800 451 624 for further vaccine booking support.

Sydney WorldPride 2023

Anyone due their second dose who received their first dose at a temporary vaccination clinic established for Sydney WorldPride – The Prevention Hub in Surry Hills or St Vincent’s Hospital WorldPride Hub in Darlinghurst – will need to call one of the clinics listed on this page to book their second dose, if they haven't been contacted already. People can also choose to walk in.

Information about the JYNNEOS vaccine

The main vaccine against mpox available in Australia is called JYNNEOS.

It is safe to use for people aged over 18 years, including people who are immunocompromised and people who have HIV. It can be given at the same time as most other vaccines.

JYNNEOS is a new vaccine so we’re still learning about it, however information from clinical trials shows the vaccine should be effective in preventing mpox.

Two doses of the vaccine are required for maximum protection, given at least 28 days apart.

The vaccine is most effective two weeks after the second dose and gives an 80% protection against mpox.

People who have an anaphylactic allergy to any of the following should not receive a JYNNEOS vaccine:

  • Benzonase
  • Ciprofloxacin
  • Gentamicin.

The JYNNEOS vaccine does not transmit mpox or any other virus to other people.

For more information visit Australian Department of Health - Monkeypox (MPX) – Information on JYNNEOS vaccine.

Vaccine administration

The JYNNEOS vaccine will only be given subcutaneously (under the skin) by trained staff rather than intradermally (into the outer layers of the skin).

Anyone who received their first dose of the JYNNEOS vaccine intradermally can safely receive their second dose subcutaneously.

The decision to switch to subcutaneous vaccination was made in January 2023 because:

  • there is now a good supply of the vaccine available in NSW (intradermal vaccination was introduced to allow more people to get vaccinated when there were only limited supplies of vaccine, as intradermal vaccination requires a lower dose of vaccine than subcutaneous vaccination)
  • there is a slightly higher risk of skin discolouration with intradermal vaccination than subcutaneous vaccination
  • administering an intradermal vaccination is a specialised technique that requires additional training
  • administration of the vaccination on the forearm (for intradermal vaccination) is less likely to be hidden by clothing than administration on the upper arm (for subcutaneous vaccination) and this can be a barrier to vaccination for some people.

Vaccine side effects

As with all vaccines, minor side effects can be expected with the JYNNEOS vaccine. Most are mild and short-lived.

Common side effects include:

  • minor redness
  • pain or swelling at the injection site
  • tiredness, headache, muscle pain or fever.

People with eczema may experience more symptoms after vaccination compared to those without this condition.

Read our post-vaccination fact sheet for more information on what to expect after getting your JYNNEOS vaccine.

Seven days after you receive your vaccine, you will receive an email or SMS by AusVaxSafety. You will be contacted three times in total and asked to complete an anonymous survey to report any symptoms. The survey is voluntary and will contribute to the national mpox vaccine safety surveillance. If you don’t want to participate, please ignore the SMS or emails or unsubscribe.

Advice for people who have had mpox

At this stage, vaccination is not required if you have been diagnosed with mpox.

Previous research in cases who have been infected with similar viruses suggests long-term immunity after infection. However, we do not yet have a clear understanding of this with the mpox virus, including to what extent you will be protected and if so, for how long.

Therefore, it is important to take necessary precautions to protect yourself to avoid being reinfected again. Read our Information for people who have mpox for further guidance.

Advice for people who have been exposed to mpox

High-risk contacts will be offered the JYNNEOS vaccine as post-exposure prophylaxis (PEP), ideally within 4 days but up to 14 days post exposure to mpox.

Medium-risk contacts may be offered this too, but the local public health unit will advise further.

Read our Information for high-risk contacts and Information for medium-risk contacts for further advice.

Pregnancy and vaccination

The JYNNEOS vaccine is safe and preferred for those who are pregnant or breastfeeding.

Do you have more questions?

For answers to other frequently asked questions, visit ACON - Frequently asked questions about mpox.

Staying safe and preventing the spread

Vaccination is only one way to prevent mpox infection.

As there is still a risk of infection following vaccination, it’s still important to take steps to reduce the chance of catching or spreading mpox.

For advice on how to stay safe and prevent mpox infection, visit the mpox information hub or our partner ACON.


Translated mpox fact sheets and resources are available in multiple languages:

  • Arabic / العربية
  • Simplified Chinese / 简体中文
  • Traditional Chinese / 繁體中文
  • Portuguese / Português
  • Spanish / Español
  • Thai / ภาษาไทย
  • Vietnamese / Tiếng Việt Nam

For free help in your language, call the Translating and Interpreting Service on 13 14 50.

Current as at: Monday 1 May 2023
Contact page owner: Communicable Diseases