The JYNNEOS vaccine to protect against mpox (monkeypox) is free in NSW for eligible groups of people. You can be vaccinated without a Medicare card.

People who are recommended to be vaccinated against mpox can make an appointment using our online booking system or call the clinic for booking support.

For free help in your language, call the Translating and Interpreting Service on 13 14 50.

On this page

Who should be vaccinated?

The following people are recommended to be vaccinated against mpox:

  • all sexually active gay and bisexual men (cis and trans)
  • sexual partners of the people above
  • sex workers.

If this criteria applies to you, you can book your vaccine at one of the clinics listed below.

Anyone who has already received their first dose is recommended to receive their second dose if it is at least 28 days since their first dose.


If you recently received your first dose of vaccine and have a second dose appointment scheduled at either The Prevention Hub in Surry Hills after 18 March 2023 or St Vincent’s Hospital WorldPride Hub in Darlinghurst after 10 March 2023 – you will be contacted by clinic staff to reschedule your appointment.

In the unlikely event that you were uncontactable by clinic staff, you will need to book in a ‘second dose only’ appointment. To book your second dose appointment either call one of the clinics directly or use the links provided in the table below.

Book an appointment

Search for your nearest vaccination clinic in the list below.

If you are having trouble booking an appointment, call the vaccination clinic if they have a contact phone number. You can also call Sexual Health Infolink on 1800 451 624 for further vaccine booking support.

Sydney - Metro

City/suburbVaccination centre/clinicFor booking support
Blacktown Make a booking at Blacktown NSW Health Monkeypox Vaccination Centre(02) 9881 8000 Monday to Friday
Camperdown Make a booking at RPA NSW Health Monkeypox Vaccination Centre1800 955 566
Camperdown Call RPA Sexual Health Clinic, 16 Marsden Street, Camperdown to make a booking(02) 9515 1200
DarlinghurstCall Kirketon Road Centre, above the Darlinghurst Fire Station, Victoria Street (entrance), Darlinghurst to make a booking(02) 9360 2766
Darlinghurst Call IBAC Clinic, St Vincent's Hospital, Level 4, Xavier Building, 390 Victoria Street, Darlinghurst to make a booking

(02) 8382 3707

Kogarah Call Short Street Centre Sexual Health Clinic, St George Hospital
Ground Floor, Prichard Wing Short Street, Kogarah to make a booking
(02) 9113 2742
KingswoodCall the Nepean Sexual Health Clinic to make a booking(02) 4734 2507
Liverpool Make a booking at Liverpool NSW Health Monkeypox Vaccination Centre0457 190 556
Parramatta Call Western Sydney Sexual Health Centre, Parramatta Health Service, 162 Marsden Street, Parramatta to make a booking

(02) 9843 3124

Surry HillsCall The Albion Centre, 150-154 Albion Street, Surry Hills to make a booking

(02) 9332 9600

St Leonards Make a booking at St Leonards NSW Health Monkeypox Vaccination Clinic(02) 9462 9500
Sydney CBDCall Sydney Sexual Health Clinic, Level 3, Nightingale Wing, Sydney Eye Hospital, 8 Macquarie Street, Sydney to make a booking

(02) 9382 7440

NSW - Central Coast

City/suburbVaccination centreFor booking support
Gosford Make a booking at Gosford NSW Health Monkeypox Vaccination Centre(02) 4320 2114

NSW - Far West

City/suburbVaccination centreFor booking support
Broken Hill Make a booking at Broken Hill NSW Health Monkeypox Vaccination Centre(08) 8080 1100
Far West (Mobile Clinic)For bookings outside of Broken Hill, contact Broken Hill Community Health Centre(08) 8080 1100

NSW - Hunter New England

City/suburbVaccination clinicFor booking support
NewcastleCall Pacific Clinic, Newcastle Sexual Health, Level 2, 670 Hunter Street, Newcastle to make a booking(02) 4016 4536

Make a booking at Tamworth NSW Health Monkeypox Vaccination Clinic

(02) 6764 8080
Taree Make a booking at Taree NSW Health Monkeypox Vaccination Clinic(02) 6515 1947
Wallsend Make a booking at Wallsend NSW Health Monkeypox Vaccination Centre1800 570 575

NSW - North

City/suburbVaccination clinicFor booking support
LismoreCall Lismore Sexual Health Service, 4 Shepherd Lane, Lismore to make a booking(02) 6620 2980
Tweed HeadsCall Tweed Valley Sexual Health Service (Clinic 145), 145 Wharf Street, Tweed Heads to make a booking

(07) 5506 6850

NSW - North Coast

City/suburbVaccination clinicFor booking support
Coffs HarbourCall Sexual Health Clinic (Clinic 916), Coffs Harbour Health Campus, 345 Pacific Highway to make a booking(02) 6656 7865
Port Macquarie Call Sexual Health (Clinic 33), Port Macquarie Community Health Centre, Morton Street to make a booking(02) 6589 2120
Select option 2 then option 6

NSW - South

City/suburbVaccination clinicFor booking support
Albury Make a booking at Albury NSW Health Monkeypox Vaccination Clinic(02) 6058 1831
Wagga Wagga Make a booking at Wagga Wagga NSW Health Monkeypox Vaccination Clinic(02) 5943 2830
Queanbeyan Make a booking at Queanbeyan NSW Health Monkeypox Vaccination Clinic0427 893 247

NSW - South Coast

City/suburbVaccination clinicFor booking support
Port KemblaCall Illawarra Shoalhaven Sexual Health Service, Port Kembla Hospital to make a booking(02) 4223 8457
Eurobodalla Make a booking at Eurobodalla NSW Health Monkeypox Vaccination Clinic0427 219 874
Bega Make a booking at Bega NSW Health Monkeypox Vaccination Clinic0427 219 874
Batemans Bay Make a booking at Batemans Bay NSW Health Monkeypox Vaccination Clinic

0427 219 874

NSW - West

City/suburbVaccination clinicFor booking support
Dubbo Make a booking at Dubbo NSW Health Monkeypox Vaccination ClinicTBC
Griffith Make a booking at Griffith NSW Health Monkeypox Vaccination Clinic(02) 6966 9900
Orange Make a booking at Orange NSW Health Monkeypox Vaccination ClinicTBC

About mpox (monkeypox)

What is mpox?

Mpox is caused by a virus that is spread mainly through skin-to-skin contact, or close contact with someone who has mpox. In NSW, it is primarily affecting gay and bisexual men and other men who have sex with men. For more information, visit our mpox information hub.

NSW JYNNEOS vaccine rollout

NSW Health began vaccinating people at highest risk from mpox on 8 August 2022.

NSW Health is working closely with partner agencies such as NSW Sexual Health Infolink and ACON on the vaccine rollout.

People who are recommended to receive the vaccine can book and manage their appointments online, or can call a clinic for booking support.

Anyone who is having issues with viewing or changing their booking online should call the clinic they have an appointment with or NSW Sexual Health Infolink on 1800 451 624.

The JYNNEOS vaccine to protect against mpox is free in NSW and you can be vaccinated without Medicare.

Sydney WorldPride 2023

All eligible international and interstate visitors were able to access the vaccine for free while they were in NSW for Sydney WorldPride. Anyone who received their first dose in Sydney and then travelled after Sydney WorldPride are able to get their second dose at a different clinic in NSW.

If you’re travelling to another state or country after Sydney WorldPride, you will need to get your second dose there but check the eligibility criteria as this may be different to NSW.

Anyone due their second dose who received their first dose at a temporary vaccination clinic established for Sydney WorldPride – The Prevention Hub in Surry Hills or St Vincent’s Hospital WorldPride Hub in Darlinghurst – will need to book into one of the ‘second dose only’ clinics listed above. This is because these two Sydney WorldPride clinics were temporary. To book your second dose, book online or call one of the clinics in the table above or you can walk-in.

Information about the JYNNEOS vaccine

The main vaccine against mpox available in Australia is called JYNNEOS.

It is safe to use for people aged over 18 years, including people who are immunocompromised and people who have HIV. It can be given at the same time as most other vaccines.

JYNNEOS is a new vaccine so we’re still learning about it, however information from clinical trials shows the vaccine should be effective in preventing mpox.

Two doses of the vaccine are required for maximum protection, given at least 28 days apart.

The vaccine is most effective two weeks after the second dose and gives an 80% protection against mpox.

People who have an anaphylactic allergy to any of the following should not receive a JYNNEOS vaccine:

  • Benzonase
  • Ciprofloxacin
  • Gentamicin.

The JYNNEOS vaccine does not transmit mpox or any other virus to other people.

For more information visit Australian Department of Health - Monkeypox (MPX) – Information on JYNNEOS vaccine.

Vaccine administration

The JYNNEOS vaccine will now only be given subcutaneously (under the skin) by trained staff rather than intradermally (into the outer layers of the skin).

Anyone who received their first dose of the JYNNEOS vaccine intradermally can safely receive their second dose subcutaneously.

The decision to switch to subcutaneous vaccination was made in January 2023 because:

  • there is now a good supply of the vaccine available in NSW (intradermal vaccination was introduced to allow more people to get vaccinated when there were only limited supplies of vaccine, as intradermal vaccination requires a lower dose of vaccine than subcutaneous vaccination)
  • there is a slightly higher risk of skin discolouration with intradermal vaccination than subcutaneous vaccination
  • administering an intradermal vaccination is a specialised technique that requires additional training
  • administration of the vaccination on the forearm (for intradermal vaccination) is less likely to be hidden by clothing than administration on the upper arm (for subcutaneous vaccination) and this can be a barrier to vaccination for some people.

Vaccine side effects

As with all vaccines, minor side effects can be expected with the JYNNEOS vaccine. Most are mild and short-lived.

Common side effects include:

  • minor redness
  • pain or swelling at the injection site
  • tiredness, headache, muscle pain or fever.

People with eczema may experience more symptoms after vaccination compared to those without this condition.

Read our post-vaccination fact sheet for more information on what to expect after getting your JYNNEOS vaccine.

Seven days after you receive your vaccine, you will receive an email or SMS by AusVaxSafety. You will be contacted three times in total and asked to complete an anonymous survey to report any symptoms. The survey is voluntary and will contribute to the national mpox vaccine safety surveillance. If you don’t want to participate, please ignore the SMS or emails or unsubscribe.

Advice for people who have had mpox

At this stage, vaccination is not required if you have been diagnosed with mpox.

Previous research in cases who have been infected with similar viruses suggests long-term immunity after infection. However, we do not yet have a clear understanding of this with the mpox virus, including to what extent you will be protected and if so, for how long.

Therefore, it is important to take necessary precautions to protect yourself to avoid being reinfected again. Read our Information for people who have mpox for further guidance.

Advice for people who have been exposed to mpox

High-risk contacts will be offered the JYNNEOS vaccine as post-exposure prophylaxis (PEP), ideally within 4 days but up to 14 days post exposure to mpox.

Medium-risk contacts may be offered this too, but the local public health unit will advise further.

Read our Information for high-risk contacts and Information for medium-risk contacts for further advice.

Pregnancy and vaccination

The JYNNEOS vaccine is safe and preferred for those who are pregnant or breastfeeding.

Do you have more questions?

For answers to other frequently asked questions, visit ACON - Frequently asked questions about mpox.

Staying safe and preventing the spread

Vaccination is only one way to prevent mpox infection.

As there is still a risk of infection following vaccination, it’s still important to take steps to reduce the chance of catching or spreading mpox.

For advice on how to stay safe and prevent mpox infection, visit the mpox information hub or our partner ACON.


Translated mpox fact sheets and resources are available in multiple languages:

  • Arabic / العربية
  • Simplified Chinese / 简体中文
  • Traditional Chinese / 繁體中文
  • Portuguese / Português
  • Spanish / Español
  • Thai / ภาษาไทย
  • Vietnamese / Tiếng Việt Nam

For free help in your language, call the Translating and Interpreting Service on 13 14 50.

Current as at: Tuesday 21 March 2023
Contact page owner: Communicable Diseases