Childhood vaccination safety

A young, smiling Asian boy with a party blower. Vaccines are safe

All vaccines approved for use in Australia have undergone rigorous testing to ensure they are safe and effective.

A vaccine must pass clinical trial phases before it can be registered with the Therapeutic Goods Administration (TGA).

Even once a vaccine has been approved by the TGA, it continues to be monitored closely to ensure the safety and well-being of all Australians.

Read more information about how vaccines are developed, tested and monitored.

Side effects and reactions are rare

Some children may experience a reaction to a vaccine, but serious side effects or allergic reactions are rare. The risk from vaccine-preventable diseases is far greater than the risk from vaccines.

Minor side effects can include a mild fever and pain at the injection site. If you have concerns, ask your doctor or healthcare professional.

Visit Sharing Knowledge About Immunisation (SKAI) to read more about vaccine safety or side effects.

The National Immunisation Schedule also includes a comparison table of possible vaccine side effects and the effects of the diseases they protect against.

Current as at: Friday 6 March 2026
Contact page owner: Immunisation